Predictive value of lung function measures for cardiovascular risk: A large prospective cohort study
This study examined the relationship between lung function measures and cardiovascular disease outcomes in 308,415 participants enrolled in the UK Biobank study.
Isolated small airways obstruction predicts future chronic airflow obstruction: A multinational longitudinal study
This study evaluated whether the presence of isolated small airways obstruction was associated with progression to chronic airflow obstruction in 3957 individuals enrolled in a multinational observational cohort study (BOLD) and in 26,512 participants enrolled in the UK Biobank study.
Ethnic variation in asthma phenotypic presentation and outcomes: A cross-sectional analysis of the UK Biobank
This study examined ethnic differences in the characteristics and outcomes of 31,875 people with doctor-diagnosed asthma enrolled in the UK Biobank.
This analysis compared participant characteristics and primary outcomes from individuals who were enrolled in the CAPTURE study before versus after the COVID-19 pandemic.
Investigating the impact of London’s ultra low emission zone on children’s health: Children’s health in London and Luton (CHILL) protocol for a prospective parallel cohort study
This paper described the rationale for and design of a prospective, two-arm, longitudinal cohort study that will evaluate the impact of London’s ultra-low-emission zone on children’s health.
Effects of cigarette package colors and warning labels on Marlboro smokers’ risk beliefs, product appraisals, and smoking behavior: a randomized trial
This factorial, randomized study evaluated the impact of package color and warning labels on risk beliefs, subjective ratings, and smoking behavior in 180 adult cigarette smokers.
Varenicline combined with oral nicotine replacement therapy and smartphone-based medication reminders for smoking cessation: Feasibility randomized controlled trial
This study examined the effects of varenicline alone or in combination with oral nicotine replacement therapy, each given with or without smartphone medication reminders, on pharmacotherapy adherence and smoking abstinence in 34 adults enrolled in a smoking cessation program.
Prevalence of microspirometry-defined chronic obstructive pulmonary disease in two European cohorts of patients with significant smoking history hospitalised for acute myocardial infarction
This study evaluated the prevalence of COPD in two cohorts of patients with a smoking history of ≥10 pack‑years who had been hospitalized for acute myocardial infarction.
A diagnostic challenge in an adolescent with collagen VI-related myopathy and emotional disorder–Case report
This case report describes the diagnosis of an intermediate form of collagen VI-related myopathy in a 12-year-old girl presenting with morning headache, irritability, and aggressiveness.
This study quantified spontaneous cough frequency in 79 healthy adult volunteers aged 20–74 years.
Risk factors for chronic obstructive pulmonary disease (COPD) in a tertiary health institution in Lagos, Nigeria
This cross-sectional study examined clinical characteristics and identifiable risk factors in 79 patients with spirometry-confirmed COPD at a tertiary health clinic in Lagos, Nigeria.
Comparison of pneumotachometer and portable digital turbine spirometry for field-based assessment: An air quality, environment, and respiratory outcomes in bronchopulmonary dysplasia study
This cross-sectional, field-based analysis evaluated the use of remote spirometry in 21 pediatric patients aged 6–12 years with a history of bronchopulmonary dysplasia.
Efficacy and tolerability of gefapixant for treatment of refractory or unexplained chronic cough: A systematic review and dose-response meta-analysis
This systematic review and dose-response meta-analysis evaluated the efficacy and tolerability of gefapixant for the treatment of adults with refractory or unexplained chronic cough.
This cross-sectional study examined the impact of chronic exposure to biomass fuel smoke on the respiratory health of 661 children under 15 years of age in urban and rural settings in Madagascar.
Randomised controlled trial testing effectiveness of feedback about lung age or exhaled CO combined with very brief advice for smoking cessation compared to very brief advice alone in North Macedonia: Findings from the Breathe Well group
This multicenter, randomized trial examined the effectiveness and cost-effectiveness of lung age or exhaled carbon monoxide feedback combined with very brief advice to prompt smoking cessation, as compared with very brief advice alone, in 1368 smokers in North Macedonia.
Pulmonary function parameters in relation to specific and generic aerobic muscle capacities in recreational and disabled post-COVID-19 swimmers
This study assessed the pulmonary function of 21 individuals with long COVID conditions who were enrolled in a water-based exercise program designed to improve pulmonary function.
Reduced lung function and cause-specific mortality: A population-based study of Norwegian men followed for 26 years
This study examined the association between different spirometric patterns and cause of death in 26,091 men aged 30–46 years who participated in the Pneumoconiosis Survey of Western Norway between 1988 and 1990.
This multicenter study, conducted in a cohort of 191 patients with COPD, examined provider- and participant-reported medication concordance, and its impact on clinical management.
Validation of a novel vocal demand task for measuring vocal fatigue: The fluid interval test for voice (FIT-V)
This thesis described outcomes of a repeated-measures study designed to validate a novel vocal demand task in 30 young-to-early-middle-aged, vocally healthy and vocally untrained individuals.
This retrospective cohort study evaluated the relationship between a restrictive spirometry pattern and the risk of death in 4315 adult patients diagnosed with silicosis.
Reference lung function of Nigerian school-age children measured with electronic peak flow meter: Comparison with local and Global-Lung-Initiative equations
This cross-sectional study examined PEF and FEV1 values in 766 healthy Nigerian school children aged 6–11 years, including the suitability of local and GLI reference equations in this population.
This study evaluated the association between salivary DNA methylation levels and cognitive performance in 56 current smokers and ex-smokers aged 25–55 years.
Repurposing catheter ablation work-up to detect expiratory airflow limitation in patients with atrial fibrillation
This prospective study evaluated the diagnostic value of repurposing existing pre-surgical assessments to identify airflow limitation in patients (n=110) with atrial fibrillation scheduled for catheter ablation.
This prospective, cross‐sectional study examined the utility of lower-frequency forced oscillation technique indices in 45 children and adults with cystic fibrosis of varying severity.
Relative bioavailability of budesonide/glycopyrrolate/formoterol fumarate triple therapy delivered using next generation propellants with low global warming potential
This randomized, single-blind, single-dose, 3-period crossover study evaluated the relative bioavailabilities of budesonide, glycopyrrolate, and formoterol fumarate when delivered as triple therapy via pMDIs that used different propellant formulations.
Associations of healthy aging index and all-cause and cause-specific mortality: A prospective cohort study of UK Biobank participants
This study examined the association between the Healthy Aging Index and mortality in 387,794 individuals enrolled in the UK Biobank.
This review examined the features of refractory chronic cough, including risk factors, pathophysiology, assessment, and available pharmacological and non-pharmacological treatments.
Comparison of the Bluetooth iCOquit, piCO, and Vitalograph for the assessment of breath carbon monoxide among adults initiating smoking cessation and standardized canisters
This randomized study examined the validity of different CO monitors for the assessment of breath CO levels in 93 adults initiating smoking cessation treatment.
Relationship between early life asthma and chronic airway disease in adult life – In search for disease trajectories over the life span – The RELATE study based on the Kongsberg cohort
This paper describes the design and methodology of a study designed to evaluate the relationship between severe childhood asthma and obstructive lung disease in adulthood.
This review examined current challenges and opportunities in the early detection of COPD, including the use of COPD case-finding as an efficient means of identifying at-risk COPD patients.
Unsupervised home spirometry is not equivalent to supervised clinic spirometry in children and young people with cystic fibrosis: Results from the CLIMB-CF study
The CLIMB‐CF study explored the feasibility and acceptability of home monitoring of children and young people with cystic fibrosis, including whether values collected during home spirometry were interchangeable with traditional, clinic‐based spirometry.
This study used data from a cluster randomized controlled trial to establish the best combination of measures to optimize the diagnosis of COPD in a primary care setting; the study was conducted in 335 current or ex-smokers, including patients with established COPD.
Causal inverse association between lung function and new-onset microvascular diseases in patients with type 1 diabetes
This study examined the relationship between lung function and microvascular disease in individuals with diabetes, type 2 diabetes mellitus, and type 1 diabetes mellitus.
Right inferior frontal gyrus theta-burst stimulation reduces smoking behaviors and strengthens fronto-striatal-limbic resting-state functional connectivity: A randomized crossover trial
This double-blind, randomized, crossover study examined effects of neuromodulation of the right inferior frontal gyrus on smoking behavior in 31 nicotine-dependent adults.
Lungs function in relation to exposure to cotton dust in a hosiery section of a textiles plant in Punjab, Pakistan
This cross-sectional study examined the effects of cotton dust on the respiratory health of 287 workers employed in the hosiery section of a textiles plant in Faisalabad, Pakistan.
Associations of DHEA(S) with negative and positive affect in people who smoke daily with elevated and low depression symptoms: A pilot laboratory study
This study examined the association between DHEA(S) levels and negative and positive affect in 88 regular cigarette smokers with elevated depression symptoms.
Preserved ratio impaired spirometry and risks of macrovascular, microvascular complications and mortality among individuals with type 2 diabetes
This study examined the relationship between PRISm and new-onset macrovascular and microvascular complications and mortality in individuals with type 2 diabetes.
Short-term effects of the chemical components of fine particulate matter on pulmonary function: A repeated panel study among adolescents
This study used data from a repeated panel study to examine the relationship between the concentration of PM2.5 chemical components and pulmonary function in 47 adolescents living on Yuge Island, western Japan.
This cross-sectional, case-control study conducted in 100 individuals compared lung function in patients with type 2 diabetes mellitus versus normal healthy control subjects.
Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease
This study examined the change over time in cognitive function and the risk of incident dementia in 3,982 older adults with COPD enrolled in a population-based cohort study in Sweden.
Patient characteristics to consider when selecting an inhaler for the treatment of chronic obstructive pulmonary disease and available assessment methods: A narrative review
This narrative review outlined patient characteristics known to impact correct inhaler use, and available tools for the assessment of correct inhaler use.
This study compared pulmonary function in 100 smokers versus non-smokers.
Objective and self-reported evidence of dextromethorphan antitussive efficacy in children, aged 6–11 years, with acute cough due to the common cold
This multiple‐dose, double‐blind, placebo‐controlled, randomized trial was undertaken to establish the most suitable objective and subjective endpoints for evaluating the anti-tussive efficacy of dextromethorphan hydrobromide; the study included 128 children aged 6–11 years with cough due to the common cold.
This randomized, double-blind, placebo-controlled, crossover trial evaluated the efficacy and safety of nalbuphine extended-release tablets for the treatment of cough in 41 in patients with IPF.
This cross-sectional study compared lung volume responses in 1500 child athletes and non-athletes aged 8–18 years.
The association of denture wearing with reduced lung function and increased airflow limitation in 58–72 year old men
This prospective case-control study examined the association between denture wearing and airflow limitation in 706 men aged 58–72 years living in Northern Ireland.
This study examined the relationship between lung function and cognitive ability in children enrolled in the ALSPAC birth cohort.
This study used data from 65,145 individuals enrolled in the UK Biobank to identify occupational risk factors for small airway obstruction. Spirometric endpoints included FEV1, FVC, and FEV1/FVC ratio, which were measured using a calibrated Vitalograph Pneumotrac spirometer.
Clinical performance of spirometry and respiratory oscillometry for prediction of severe exacerbations in school children with asthma
This study prospectively evaluated the performance of spirometry and respiratory oscillometry for predicting severe asthma exacerbations in 148 asthmatic children aged 6–14 years.
Efficacy and safety of eliapixant in refractory chronic cough: The randomized, placebo-controlled Phase 2b PAGANINI study
This randomized, double-blind, parallel-group, placebo-controlled, multicenter, dose-finding, Phase 2b study evaluated the efficacy and safety of eliapixant in 310 adult patients with refractory chronic cough.
This cross-sectional study analyzed the clinical characteristics and risk factor profiles of 323 outpatients with COPD aged ≥30 years in Kampala, Uganda.
Efficacy and Safety of Pharmacotherapy for Refractory Chronic Cough: A Systematic Review and Network Meta-Analysis
This systematic review and network meta-analysis examined the efficacy and safety of pharmacotherapy for the treatment of refractory chronic cough in 19 randomized controlled trials.
Association of preserved ratio impaired spirometry with airflow obstruction and mortality among silicotic patients: A cohort study
This retrospective cohort study examined the relationship between PRISm, airflow obstruction, and mortality in 4315 silicotic patients in Hong Kong.
This longitudinal cohort study evaluated the relationship between subgingival microbial diversity and respiratory function in 507 dentate men aged 58–72 years in Northern Ireland.
This review outlined the various methods used to measure cough, including subjective and objective approaches.
Effects of hyperventilation on oxygenation, apnea breaking points, diving response, and spleen contraction during serial static apneas
This study examined the effect of hyperventilation, as compared with normal breathing, on oxygenation, apnea breaking points, diving response, and splenic contraction during serial breath-holding in 18 volunteers with little or no experience in freediving.
Deep transfer learning for chronic obstructive pulmonary disease detection utilizing electrocardiogram signals
This study examined the feasibility of using deep transfer learning frameworks to detect COPD based on ECG data.
Efficacy of oral nalbuphine extended release in patients with idiopathic-pulmonary-fibrosis-related chronic cough: A Phase 2 study
This randomized, double-blind, Phase 2 crossover trial compared the efficacy of extended-release oral nalbuphine versus placebo in 42 patients with IPF-related chronic cough.
A single center observational study of spirometry assessments in children with congenital heart disease after surgery
This retrospective study compared pulmonary function following open-heart surgery in 86 children with various forms of congenital heart disease.
Evaluation of ocular microvascular characteristics in smokers and patients with chronic obstructive pulmonary disease using an optical coherence tomography angiography
This prospective study used using optical coherence tomography angiography to assess the retinal vasculature of patients with COPD (n=38), as compared with measurements in smokers (n=30) and healthy non-smokers (n=30).
Development and validation of a simple general population lung cancer risk model including AHRR-methylation
This study aimed to develop and validate a model for predicting the 10-year risk of lung cancer in more than 10,500 former or current smokers who participated in the 1991–1994 and 2001–2003 follow-up examinations of the Copenhagen City Heart Study.
Asthma control and care among six public health clinic attenders in Malaysia: A cross-sectional study
This cross‐sectional study examined risk factors for poor disease control and patterns of care in 1280 adult and children with asthma in the Klang District, Malaysia.
Efficacy and safety of combination behavioral activation for smoking cessation and varenicline for treating tobacco dependence among individuals with current or past major depressive disorder: A 2 × 2 factorial, randomized, placebo-controlled trial
This randomized, placebo-controlled study examined the efficacy and safety of behavioral activation for smoking cessation versus standard behavioral treatment (with each treatment administered in combination with placebo or varenicline) in 300 adult smokers with current or past major depressive disorder.
10-year follow-up of the original Faroese septuagenarian cohort: Focus on frailty and association with all-cause mortality
This population-wide study examined the health status of 347 older adults (mean age 82.5 years) included in the Faroese Septuagenarian Cohort established in 2007/2008.
This cross-sectional study evaluated the feasibility of respiratory oscillometry in 154 school children aged 6 to 14 years with asthma.
This study evaluated the prevalence of airflow limitation in 610 individuals who participated in a community-based screening program in Singapore.
This review outlined the most widely used subjective and objective methods for measuring cough, including an overview of their advantages and limitations for use in both research and clinical practice.
This study comprised a preliminary assessment of a low-cost, open-source spirometer developed using readily available electronic components and sensors.
This study investigated the relationship between different dietary patterns in mid-childhood and lung function and incident asthma in adolescence using data from 2,950−4,491 children enrolled in the ALSPAC population-based birth cohort.
Real-time system for monitoring the water vapour concentration and temperature of air exhaled from human lungs
This study comprised a preliminary investigation of a fully optoelectronic system designed to provide real-time measurement of water vapor concentration and temperature of air exhaled from human lungs.
Antibiotic therapy for pulmonary exacerbations in cystic fibrosis–A single-centre prospective observational study
This prospective, single center study evaluated treatment outcomes in 96 pediatric and adult patients with cystic fibrosis who received oral and/or intravenous antibiotic therapy for the management of bronchopulmonary exacerbations.
Real-life effectiveness of indacaterol/glycopyrronium/mometasone for symptomatic relief of cough after switching from inhaled corticosteroid/long-acting β2-agonist therapy in patients with asthma: REACH study design
This paper describes the design of REACH, an 8-week real-life study that will examine the efficacy of indacaterol acetate/glycopyrronium bromide/mometasone furoate, as compared with a high-dose inhaled corticosteroid/long-acting β2-agonist, in asthmatic patients with refractory cough.
This study examined the relationship between PRISm and the risk of developing type 2 diabetes, including the role of circulating metabolites in any such relationship.
The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: A randomized controlled trial
This double-blind, randomized, placebo-controlled, two-sequence, two-period crossover study evaluated the efficacy, safety, tolerability, and pharmacokinetics of ascending doses of filapixant in 23 patients with refractory chronic cough.
An investigation of latex sensitivity and respiratory complaints in workers in a rubber-based material manufacturing industry
This study examined the prevalence of latex sensitivity in 108 males in a workplace producing rubber-based vehicle seals, as compared with 52 control subjects.
An interim analysis of a Phase 2 trial evaluating oral nalbuphine extended release for treating chronic cough in idiopathic pulmonary fibrosis
This randomized, double-blind, placebo-controlled, Phase 2 crossover trial examined the use of extended-release oral nalbuphine for the treatment of chronic cough in 26 patients with idiopathic pulmonary fibrosis.
This study was undertaken to develop diagnostic thresholds for Parameter D, a novel metric for detection of airflow obstruction.
Smoking status affects cognitive, emotional and neural-connectivity response to distress-inducing auditory feedback
This study examined the relationship between distress tolerance and task-based functional connectivity in 62 individuals aged 25–55 years who were current or former smokers.
This analysis used baseline data from a prospective cohort study to examine the relationship between obstructive sleep apnea and PRISm in a community-based population of 1183 individuals aged 40–75 years in China.
Oxidative stress associated with impaired autonomic control and severity of lung function in chronic obstructive pulmonary disease patients
This study examined the association between malondialdehyde levels and pulmonary function and cardiac autonomic control in 50 patients with clinically stable COPD, as compared with 50 healthy control subjects.
Changing smoking behavior and epigenetics: A longitudinal study of 4,432 individuals from the general population
This longitudinal study examined the change in AHRR methylation over a period of approximately ten years according to smoking behaviors and demographic variables in 4432 individuals enrolled in the Copenhagen City Heart Study.
A total diet replacement weight management program for difficult-to-treat asthma associated with obesity: A randomized controlled feasibility trial
This randomized controlled single-center study compared the use of a dietitian-led total diet replacement program, as compared with usual care, for the improvement of asthma symptom and quality of life in 35 obese patients with difficult-to-treat asthma.
This cross-sectional study evaluated lung volumes among child and adolescent athletes and non-athletes aged 7–18 years in Karachi, Pakistan.
This case report described the effect of a 60-minute session with the EXOPULSE Mollii suit on pain perception, muscle oxygenation, parasympathetic modulation, and functional outcomes in a female fibromyalgia patient.
Discriminative accuracy of the CAPTURE Tool for identifying chronic obstructive pulmonary disease in US primary care settings
This cross-sectional study examined the operating characteristics of the CAPTURE screening tool for identifying patients with undiagnosed, clinically significant COPD in a primary care setting in the United States; in total, 4679 individuals aged 45–80 years were enrolled, all of whom had no previous diagnosis of COPD.
Novel capsaicin cough endpoints effectively discriminate between healthy controls and patients with refractory chronic cough
This dose-response study evaluated capsaicin-evoked cough responses and the discriminatory ability of novel cough endpoints in 93 healthy volunteers and 51 patients with refractory chronic cough.
This hospital-based cross-sectional study examined the diagnostic applicability of a minispirometer or a peak flow meter, as compared with standard spirometry, in 360 patients with asthma and COPD in Trivandrum, South India.
Impact of psychological factors on functional performance among patients with chronic obstructive pulmonary disease
This cross-sectional study examined the effects of anxiety, depression, and health-related quality of life on the functional performance of 70 clinically stable patients with COPD in Riyadh, Saudi Arabia.
An aerosol inhalation monitor would improve the accuracy of checklist assessment in drug inhalation techniques
This study evaluated inhalation skills with a pressurized MDI and two DPIs in 53 subjects, with key inhalation steps assessed using either a checklist or the Vitalograph AIM.
Resistance training of peripheral muscles benefits respiratory parameters in older women with sarcopenia: Randomized controlled trial
This randomized study evaluated the efficacy of high-intensity resistance training, as compared with no specific intervention, on clinical parameters of respiratory function and health-related quality of life in 51 community-dwelling older women (age ≥70 years) with sarcopenia.