Clinical characteristics, urinary leukotriene E4 levels, and aspirin desensitization results in patients with NSAID-induced blended reactions

This study investigated clinical patterns of NSAID sensitivity and the diagnostic roles of uLTE4 measurement in the various sensitivity phenotypes in 92 adult patients with cross-reactive NSAID hypersensitivity in Thailand. A subset of patients (n=52) underwent aspirin provocation; FEV1 was measured in these patients using a Vitalograph spirometer.