Quality of spirometry and diffusion of the lung (DLCO) data in patients with systemic sclerosis

This study examined the achievement of ATS/ERS 2005 quality standards for FVC and DLCO (ie acceptability and repeatability >85%) over a period of 48 weeks in 210 patients with active and progressive systemic sclerosis enrolled in a clinical trial. FEV1 was assessed using a Vitalograph COMPACT spirometer and analyzed using Spirotrac software.