Aprepitant for cough in lung cancer: A randomised placebo-controlled trial and mechanistic insights

Disease Areas:
Lung cancer,Cough
Device Types:
VitaloJAK

This was a randomized, double-blind, crossover trial that evaluated the efficacy and safety of aprepitant in 20 lung cancer patients with cough. The primary endpoint was awake cough frequency collected using the Vitalograph VitaloJAK device; other endpoints included night-time and 24-hour cough frequency. Secondary endpoints included patient-reported changes in cough severity, cough frequency, and cough-related QoL.

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