Spleen size and function in Sherpa living high, Sherpa living low and Nepalese lowlanders

This study examined the spleen response and the cardiovascular diving response, which are potential physiological defense mechanisms against hypoxia, in male Sherpa living at high altitudes (n=21) and low altitudes (n=7), as compared with native Nepalese lowlanders (n=10). VC was measured using the Vitalograph COMPACT spirometer.