Domiciliary diurnal variation of exhaled nitric oxide fraction for asthma control

This study evaluated whether domiciliary daily home FeNO monitoring was useful as an index of asthma control in 50 asthmatic subjects (non-severe, n=22; severe, n=28), with results compared to those in 15 healthy volunteers. Endpoints of interest included diurnal variation in FeNO and PEF, ACQ score, spirometry pre- and post-salbutamol, and sputum induction. Spirometry tests were performed using a Vitalograph dry wedge spirometer.