Small reductions in FEV1/FVC And FEF25-75% constitute predictive factors for COPD development

This study examined possible predictive factors for the development of COPD in individuals aged ≥30 years from two regions of Northern Greece; overall, 3046 subjects were recruited into the study, with follow-up occurring after a period of 11 years in 872 subjects. Lung function testing (FEV1, FVC, FEV1/FVC ratio, FEF25–75) was undertaken using a Vitalograph spirometer.