Isolated small airways obstruction predicts future chronic airflow obstruction: A multinational longitudinal study

Thursday, December 21st, 2023

This study evaluated whether the presence of isolated small airways obstruction was associated with progression to chronic airflow obstruction in 3957 individuals enrolled in a multinational observational cohort study (BOLD) and in 26,512 participants enrolled in the UK Biobank study. Baseline and follow-up spirometric testing (FEV1, FVC, FEF25–75, FEV3) in the UK Biobank study was measured using a calibrated Vitalograph Pneumotrac spirometer.