Association of plasma metabolic profiling with asthma phenotypes and exacerbation

This cross-sectional analysis examined the relationship between plasma metabolites and asthma-related traits (including eosinophilic phenotypes, lung function, current wheeze, and hospitalization) in 24,925 asthmatic individuals enrolled in the UK Biobank. Lung function measures comprised FEV1, FVC, and FEV1/FVC ratio, which were captured by trained healthcare technicians and nurses using a Vitalograph Pneumotrac spirometer.